Matulane® (pronounced match-yoo-lane) belongs to a group of medicines called antineoplastic agents or chemotherapeutic agents. Matulane® is used in combination with other anticancer agents to treat adults and children with advanced Hodgkin's lymphoma (a type of blood cancer).

Matulane®, in combination with other chemotherapeutic agents, works by preventing cancer cells from growing or from forming new cancer cells. Because the growth of normal body cells may also be affected by Matulane®, side effects will often occur. Some of these may be serious and must be reported to your doctor. Matulane® comes in capsule form and is taken by mouth under medical supervision.

References:

  1. Matulane® Prescribing Information. Gaithersburg, MD: Sigma-Tau Pharmaceuticals, Inc. February 2004.

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Important Safety Information

WARNING
It is recommended that MATULANE be given only by or under the supervision of a physician experienced in the use of potent antineoplastic drugs. Adequate clinical and laboratory facilities should be available to patients for proper monitoring of treatment.

Matulane is contraindicated in patients with known hypersensitivity to the drug or inadequate marrow reserve as demonstrated by bone marrow aspiration. Due consideration of this possible state should be given to each patient who has leukopenia, thrombocytopenia, or anemia.

Matulane in combination therapy is a potent chemotherapeutic agent. Before prescribing Matulane, the sections in the Prescribing Information concerning usage in pregnancy, occurrence of secondary cancers, monitoring required in liver and kidney disease, hematologic effects, CNS effects, and potentiation associated with alcohol and MAO inhibitors should be carefully evaluated.

Please see full Prescribing Information for Matulane indications and usage, contraindications, and warnings including boxed WARNINGS, precautions, and adverse reactions.